Predicting Protein Subcellular Localization Using Abstract Sequential Features

نویسندگان

  • Adrian Silvescu
  • Cornelia Caragea
  • Vasant Honavar
چکیده

Determination of protein subcellular localization plays an important role in understanding protein function [1]. Knowledge of subcellular localization is also essential for genome annotation and drug discovery. Moreover, abnormal subcellular localization has been correlated with several diseases, such as cancer and Alzheimer’s disease. Experimental determination of protein subcellular localization is expensive and laborious. Hence, there is significant interest in the development of computational methods for reliable prediction of protein subcellular localization.

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تاریخ انتشار 2009